Tetracycline-inducible shRNA targeting long non-coding RNA PVT1 inhibits cell growth and induces apoptosis in bladder cancer cells

Recent studies show that long non-coding RNAs (lncRNAs) may be significant functional regulators in tumor development, including bladder cancer. Here, we found that PVT1 was upregulated in bladder cancer tissues and cells. Further experiments revealed that PVT1 promoted cell proliferation and suppre...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Zhuang, Chengle, Li, Jianfa, Liu, Yuchen, Chen, Mingwei, Yuan, Jiancheng, Fu, Xing, Zhan, Yonghao, Liu, Li, Lin, Junhao, Zhou, Qing, Xu, Wen, Zhao, Guoping, Cai, Zhiming, Huang, Weiren
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747399/
https://ncbi.nlm.nih.gov/pubmed/26517688
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