IDH mutation and MGMT promoter methylation in glioblastoma: results of a prospective registry

BACKGROUND: The relative contribution of isocitrate dehydrogenase mutations (mIDH) and O6-methylguanine-DNA methyltransferase promoter methylation (methMGMT) as biomarkers in glioblastoma remain poorly understood. METHODS: We investigated the association between methMGMT and mIDH with progression fr...

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Pubblicato in:Oncotarget
Autori principali: Yang, Pei, Zhang, Wei, Wang, Yinyan, Peng, Xiaoxia, Chen, Baoshi, Qiu, Xiaoguang, Li, Guilin, Li, Shouwei, Wu, Chenxing, Yao, Kun, Li, Wenbin, Yan, Wei, Li, Jie, You, Yongping, Chen, Clark C., Jiang, Tao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2015
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747376/
https://ncbi.nlm.nih.gov/pubmed/26503470
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