A biotherapy based on PSCs-in-3D spheroid-ameliorated biologics depletes in vivo cancer-sustaining stem cells

CSCs are able to survive routine anticancer procedures and peripheral-immune attack. Here we develop and detail a framework of CSC elimination governed by 3D-biologics. Pluripotent cells-engineered 3D-biologics (PMSB) and control non-3D-biologics were prepared from placenta-based somatic stem cells...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zhang, Wenhui, Yang, Huanhuan, Zhang, Yanna, Lu, Yanan, Zhou, Tianlin, Li, Meng, Wen, Yanjun, Lin, Xiaojuan, Xiang, Rong, Chen, Xiancheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747367/
https://ncbi.nlm.nih.gov/pubmed/26512920
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