Co-delivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles for the treatment of non-small lung cancer

An amphiphilic copolymer, folic acid (FA) modified poly(ethylene glycol)-poly(lactic-co-glycolic acid) (FA-PEG-PLGA) was prepared and explored as a nanometer carrier for the co-delivery of cisplatin (cis-diaminodichloroplatinum, CDDP) and paclitaxel (PTX). CDDP and PTX were encapsulated inside the h...

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Udgivet i:Oncotarget
Main Authors: He, Zelai, Huang, Jingwen, Xu, Yuanyuan, Zhang, Xiangyu, Teng, Yanwei, Huang, Can, Wu, Yufeng, Zhang, Xi, Zhang, Huijun, Sun, Wenjie
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2015
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747216/
https://ncbi.nlm.nih.gov/pubmed/26517524
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