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Lysozyme release and polymer erosion behavior of injectable implants prepared from PLGA-PEG block copolymers and PLGA/PLGA-PEG blends

PURPOSE: We evaluated the controlled release lysozyme from various poly(D,L-lactic-co-glycolic acid) (PLGA) 50/50-polyethylene glycol (PEG) block copolymers relative to PLGA 50/50. METHODS: Lysozyme was encapsulated in cylindrical implants (0.8 mm diameter) by a solvent extrusion method. Release stu...

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Detalhes bibliográficos
Main Authors: Milacic, Vesna, Schwendeman, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3930621/
https://ncbi.nlm.nih.gov/pubmed/23959854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1173-6
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