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Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma

Repeat tumor biopsies to study genomic changes during therapy are difficult, invasive and data are confounded by tumoral heterogeneity. The analysis of circulating tumor DNA (ctDNA) can provide a non-invasive approach to assess prognosis and the genetic evolution of tumors in response to therapy. Mu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Gray, Elin S., Rizos, Helen, Reid, Anna L., Boyd, Suzanah C., Pereira, Michelle R., Lo, Johnny, Tembe, Varsha, Freeman, James, Lee, Jenny H.J., Scolyer, Richard A., Siew, Kelvin, Lomma, Chris, Cooper, Adam, Khattak, Muhammad A., Meniawy, Tarek M., Long, Georgina V., Carlino, Matteo S., Millward, Michael, Ziman, Melanie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747205/
https://ncbi.nlm.nih.gov/pubmed/26524482
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