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Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma

Repeat tumor biopsies to study genomic changes during therapy are difficult, invasive and data are confounded by tumoral heterogeneity. The analysis of circulating tumor DNA (ctDNA) can provide a non-invasive approach to assess prognosis and the genetic evolution of tumors in response to therapy. Mu...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Gray, Elin S., Rizos, Helen, Reid, Anna L., Boyd, Suzanah C., Pereira, Michelle R., Lo, Johnny, Tembe, Varsha, Freeman, James, Lee, Jenny H.J., Scolyer, Richard A., Siew, Kelvin, Lomma, Chris, Cooper, Adam, Khattak, Muhammad A., Meniawy, Tarek M., Long, Georgina V., Carlino, Matteo S., Millward, Michael, Ziman, Melanie
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747205/
https://ncbi.nlm.nih.gov/pubmed/26524482
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