Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma

Repeat tumor biopsies to study genomic changes during therapy are difficult, invasive and data are confounded by tumoral heterogeneity. The analysis of circulating tumor DNA (ctDNA) can provide a non-invasive approach to assess prognosis and the genetic evolution of tumors in response to therapy. Mu...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gray, Elin S., Rizos, Helen, Reid, Anna L., Boyd, Suzanah C., Pereira, Michelle R., Lo, Johnny, Tembe, Varsha, Freeman, James, Lee, Jenny H.J., Scolyer, Richard A., Siew, Kelvin, Lomma, Chris, Cooper, Adam, Khattak, Muhammad A., Meniawy, Tarek M., Long, Georgina V., Carlino, Matteo S., Millward, Michael, Ziman, Melanie
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747205/
https://ncbi.nlm.nih.gov/pubmed/26524482
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