Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis

Palmitic acid (PA) induces hepatocyte apoptosis and fuels de novo ceramide synthesis in the endoplasmic reticulum (ER). Myristic acid (MA), a free fatty acid highly abundant in copra/palmist oils, is a predictor of nonalcoholic steatohepatitis (NASH) and stimulates ceramide synthesis. Here we invest...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Martínez, Laura, Torres, Sandra, Baulies, Anna, Alarcón-Vila, Cristina, Elena, Montserrat, Fabriàs, Gemma, Casas, Josefina, Caballeria, Joan, Fernandez-Checa, Jose C., García-Ruiz, Carmen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2015
Konular:
Research Paper: Pathology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747168/
https://ncbi.nlm.nih.gov/pubmed/26539645
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller