Lipotoxicity in steatohepatitis occurs despite an increase in tricarboxylic acid cycle activity

The hepatic tricarboxylic acid (TCA) cycle is central to integrating macronutrient metabolism and is closely coupled to cellular respiration, free radical generation, and inflammation. Oxidative flux through the TCA cycle is induced during hepatic insulin resistance, in mice and humans with simple s...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Patterson, Rainey E., Kalavalapalli, Srilaxmi, Williams, Caroline M., Nautiyal, Manisha, Mathew, Justin T., Martinez, Janie, Reinhard, Mary K., McDougall, Danielle J., Rocca, James R., Yost, Richard A., Cusi, Kenneth, Garrett, Timothy J., Sunny, Nishanth E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
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Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4824140/
https://ncbi.nlm.nih.gov/pubmed/26814015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00492.2015
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