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Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models

BACKGROUND: While many biological studies can be performed on cell-based systems, the investigation of molecular pathways related to complex human dysfunctions – e.g. neurodegenerative diseases – often requires long-term studies in animal models. The nematode Caenorhabditis elegans represents one of...

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Bibliografiske detaljer
Udgivet i:Mol Neurodegener
Main Authors: Cornaglia, Matteo, Krishnamani, Gopalan, Mouchiroud, Laurent, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin A. M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746889/
https://ncbi.nlm.nih.gov/pubmed/26858201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0083-6
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