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Automated longitudinal monitoring of in vivo protein aggregation in neurodegenerative disease C. elegans models

BACKGROUND: While many biological studies can be performed on cell-based systems, the investigation of molecular pathways related to complex human dysfunctions – e.g. neurodegenerative diseases – often requires long-term studies in animal models. The nematode Caenorhabditis elegans represents one of...

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Detalhes bibliográficos
Publicado no:Mol Neurodegener
Main Authors: Cornaglia, Matteo, Krishnamani, Gopalan, Mouchiroud, Laurent, Sorrentino, Vincenzo, Lehnert, Thomas, Auwerx, Johan, Gijs, Martin A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746889/
https://ncbi.nlm.nih.gov/pubmed/26858201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13024-016-0083-6
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