Sorting nexin 10 acting as a novel regulator of macrophage polarization mediates inflammatory response in experimental mouse colitis

In response to changes in microenvironment, macrophages polarize into functionally distinct phenotypes, playing a crucial role in the pathogenesis of inflammatory bowel disease (IBD). Here, we investigated the effects of sorting nexin 10 (SNX10), a protein involved in endosomal trafficking and osteo...

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Veröffentlicht in:Sci Rep
Hauptverfasser: You, Yan, Zhou, Chun, Li, Dong, Cao, Zhong-Lian, Shen, Weixing, Li, Wan-Zhen, Zhang, Sulin, Hu, Bin, Shen, Xiaoyan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746623/
https://ncbi.nlm.nih.gov/pubmed/26856241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20630
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