SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC

The non-receptor tyrosine kinase SRC is a key mediator of cellular protumorigenic signals. SRC is aberrantly over-expressed and activated in more than 80% of colorectal cancer (CRC) patients, therefore regulation of its stability and activity is essential. Here, we report a significant down regulati...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhang, Sulin, Yang, Zhiwen, Bao, Weilian, Liu, Lixin, You, Yan, Wang, Xu, Shao, Liming, Fu, Wei, Kou, Xinhui, Shen, Weixing, Yuan, Congmin, Hu, Bin, Dang, Wenzhen, Nandakumar, Kutty Selva, Jiang, Hualiang, Zheng, Mingyue, Shen, Xiaoyan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Translational Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138201/
https://ncbi.nlm.nih.gov/pubmed/31208298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2019.1632122
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