Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs

SOX2 is a key regulator of multiple types of stem cells, especially embryonic stem cells (ESCs) and neural progenitor cells (NPCs). Understanding the mechanism underlying the function of SOX2 is of great importance for realizing the full potential of ESCs and NPCs. Here, through genome-wide comparat...

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Bibliografiske detaljer
Udgivet i:Cell Res
Main Authors: Zhou, Chenlin, Yang, Xiaoqin, Sun, Yiyang, Yu, Hongyao, Zhang, Yong, Jin, Ying
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746607/
https://ncbi.nlm.nih.gov/pubmed/26809499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.15
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