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Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs

SOX2 is a key regulator of multiple types of stem cells, especially embryonic stem cells (ESCs) and neural progenitor cells (NPCs). Understanding the mechanism underlying the function of SOX2 is of great importance for realizing the full potential of ESCs and NPCs. Here, through genome-wide comparat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Res
Auteurs principaux: Zhou, Chenlin, Yang, Xiaoqin, Sun, Yiyang, Yu, Hongyao, Zhang, Yong, Jin, Ying
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746607/
https://ncbi.nlm.nih.gov/pubmed/26809499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.15
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