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Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs

SOX2 is a key regulator of multiple types of stem cells, especially embryonic stem cells (ESCs) and neural progenitor cells (NPCs). Understanding the mechanism underlying the function of SOX2 is of great importance for realizing the full potential of ESCs and NPCs. Here, through genome-wide comparat...

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Dettagli Bibliografici
Pubblicato in:Cell Res
Autori principali: Zhou, Chenlin, Yang, Xiaoqin, Sun, Yiyang, Yu, Hongyao, Zhang, Yong, Jin, Ying
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746607/
https://ncbi.nlm.nih.gov/pubmed/26809499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.15
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