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Bif-1 deficiency impairs lipid homeostasis and causes obesity accompanied by insulin resistance
Bif-1 is a membrane-curvature inducing protein that is implicated in the regulation of autophagy and tumorigenesis. Here, we report that Bif-1 plays a critical role in regulating lipid catabolism to control the size of lipid droplets and prevent the development of obesity and insulin resistance upon...
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| Publicat a: | Sci Rep |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4746598/ https://ncbi.nlm.nih.gov/pubmed/26857140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20453 |
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