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Bif-1 suppresses breast cancer cell migration by promoting EGFR endocytic degradation

Dysregulation of EGFR expression and signaling is well documented to contribute to disease progression and metastasis in many types of cancer including breast cancer. EGF-stimulated EGFR activation leads to receptor internalization and endocytic degradation to control EGFR-mediated signaling. This p...

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Detalhes bibliográficos
Main Authors: Runkle, Kristin B., Meyerkord, Cheryl L., Desai, Neelam V., Takahashi, Yoshinori, Wang, Hong-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414416/
https://ncbi.nlm.nih.gov/pubmed/22785202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20951
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