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Aberrant Methylation of RASSF1A Closely Associated with HNSCC, a Meta-Analysis

The RAS association domain family protein 1a (RASSF1A), a tumor suppressor gene at 3p21.3, plays a very important role in various cancers, including the head and neck squamous cell carcinoma (HNSCC). Hypermethylation of CpG islands in the RASSF1A promoter region contribute to epigenetic inactivation...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Meng, Rui-Wei, Li, Yun-Cheng, Chen, Xiong, Huang, Yang-Xin, Shi, Hao, Du, Dan-Dan, Niu, Xun, Lu, Cheng, Lu, Mei-Xia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746596/
https://ncbi.nlm.nih.gov/pubmed/26857374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20756
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