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Aberrant Methylation of MGMT Promoter in HNSCC: A Meta-Analysis
BACKGROUND: O6-methylguanine-DNA methyl-transferase (MGMT) gene, a DNA repair gene, plays a critical role in the repair of alkylated DNA adducts that form following exposure to genotoxic agents. MGMT is generally expressed in various tumors, and its function is frequently lost because of hypermethyl...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5033341/ https://ncbi.nlm.nih.gov/pubmed/27657735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163534 |
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