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Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics

Little is known regarding the effect of intestinal microbiota modifiers, such as probiotics and conventionalization with exogenous bacteria, on host hepatic drug metabolism. Therefore, the goal of this study was to determine the effect of these modifiers on the expression of various drug-metabolizin...

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Bibliografiske detaljer
Udgivet i:Drug Metab Dispos
Main Authors: Selwyn, Felcy Pavithra, Cheng, Sunny Lihua, Klaassen, Curtis D., Cui, Julia Yue
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746487/
https://ncbi.nlm.nih.gov/pubmed/26586378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.067504
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