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Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics

Little is known regarding the effect of intestinal microbiota modifiers, such as probiotics and conventionalization with exogenous bacteria, on host hepatic drug metabolism. Therefore, the goal of this study was to determine the effect of these modifiers on the expression of various drug-metabolizin...

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Publicado en:Drug Metab Dispos
Main Authors: Selwyn, Felcy Pavithra, Cheng, Sunny Lihua, Klaassen, Curtis D., Cui, Julia Yue
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746487/
https://ncbi.nlm.nih.gov/pubmed/26586378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.067504
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