By Regulating Mitochondrial Ca(2+)-Uptake UCP2 Modulates Intracellular Ca(2+)

INTRODUCTION: The possible role of UCP2 in modulating mitochondrial Ca(2+)-uptake (mCa(2+)-uptake) via the mitochondrial calcium uniporter (MCU) is highly controversial. METHODS: Thus, we analyzed mCa(2+)-uptake in isolated cardiac mitochondria, MCU single-channel activity in cardiac mitoplasts, dua...

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Publicado en:PLoS One
Autores principales: Motloch, Lukas Jaroslaw, Larbig, Robert, Gebing, Tina, Reda, Sara, Schwaiger, Astrid, Leitner, Johannes, Wolny, Martin, Eckardt, Lars, Hoppe, Uta C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746117/
https://ncbi.nlm.nih.gov/pubmed/26849136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148359
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