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UCP2 Modulates Cardioprotective Effects of Ru360 in Isolated Cardiomyocytes during Ischemia

Introduction: Ruthenium 360 (Ru360) has been shown to induce cardioprotective mechanisms in perfused hearts. The agent is a specific blocker of the main cardiac mitochondrial uptake mechanism, the mitochondrial calcium uniporter (MCU). UCP2, a mitochondrial membrane protein, which influences cardiac...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: Motloch, Lukas J., Reda, Sara, Wolny, Martin, Hoppe, Uta C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588178/
https://ncbi.nlm.nih.gov/pubmed/26248074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph8030474
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