Application of Plasma Levels of Olanzapine and N-Desmethyl-Olanzapine to Monitor Clinical Efficacy in Patients with Schizophrenia

BACKGROUND: This therapeutic drug monitoring (TDM) study aimed to determine the role of olanzapine (OLZ) and N-desmethyl-OLZ (DMO) levels in the therapeutic efficacy of OLZ in patients with schizophrenia. METHOD: Plasma concentrations of OLZ (C(OLZ)) and DMO (C(DMO)) in schizophrenic patients 12 hou...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lu, Mong-Liang, Wu, Yi-Xiu, Chen, Chun-Hsin, Kuo, Pei-Ting, Chen, Yi-Hua, Lin, Chia-Hui, Wu, Tzu-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4746067/
https://ncbi.nlm.nih.gov/pubmed/26849777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148539
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