Determination of Olanzapine and N-desmethyl-olanzapine in Plasma Using a Reversed-Phase HPLC Coupled with Coulochemical Detection: Correlation of Olanzapine or N-desmethyl-olanzapine Concentration with Metabolic Parameters

BACKGROUND: Olanzapine (OLZ) is one of the most prescribed atypical antipsychotic drugs but its use is associated with unfavorable metabolic abnormalities. N-desmethyl-olanzapine (DMO), one of the OLZ metabolites by CYP1A2, has been reported to have a normalizing action on metabolic abnormalities, b...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Lu, Mong-Liang, Lin, Chia-Hui, Chen, Yi-Chuan, Yang, Huai-Chih, Wu, Tzu-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3669135/
https://ncbi.nlm.nih.gov/pubmed/23741510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065719
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados