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Localized TRPA1 channel Ca(2+) signals stimulated by reactive oxygen species promote cerebral artery dilation

Reactive oxygen species (ROS) can have divergent effects in cerebral and peripheral circulations. We found that Ca(2+)-permeable transient receptor potential ankyrin 1 (TRPA1) channels were present and colocalized with NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) oxidase 2 (NO...

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Bibliografiske detaljer
Udgivet i:Sci Signal
Main Authors: Sullivan, Michelle N., Gonzales, Albert L., Pires, Paulo W., Bruhl, Allison, Leo, M. Dennis, Li, Wencheng, Oulidi, Agathe, Boop, Frederick A., Feng, Yumei, Jaggar, Jonathan H., Welsh, Donald G., Earley, Scott
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745898/
https://ncbi.nlm.nih.gov/pubmed/25564678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005659
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