Localized TRPA1 channel Ca(2+) signals stimulated by reactive oxygen species promote cerebral artery dilation

Reactive oxygen species (ROS) can have divergent effects in cerebral and peripheral circulations. We found that Ca(2+)-permeable transient receptor potential ankyrin 1 (TRPA1) channels were present and colocalized with NADPH (reduced form of nicotinamide adenine dinucleotide phosphate) oxidase 2 (NO...

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Detalhes bibliográficos
Publicado no:Sci Signal
Main Authors: Sullivan, Michelle N., Gonzales, Albert L., Pires, Paulo W., Bruhl, Allison, Leo, M. Dennis, Li, Wencheng, Oulidi, Agathe, Boop, Frederick A., Feng, Yumei, Jaggar, Jonathan H., Welsh, Donald G., Earley, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745898/
https://ncbi.nlm.nih.gov/pubmed/25564678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005659
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