Synthesis of new potent agonistic analogs of growth hormone-releasing hormone (GHRH) and evaluation of their endocrine and cardiac activities

In view of the recent findings of stimulatory effects of GHRH analogs, JI-34, JI-36 and JI-38, on cardiomyocytes, pancreatic islets and wound healing, three series of new analogs of GHRH(1–29) have been synthesized and evaluated biologically in an endeavor to produce more potent compounds. “Agmatine...

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Detalhes bibliográficos
Publicado no:Peptides
Main Authors: Cai, Renzhi, Schally, Andrew V., Cui, Tengjiao, Szalontay, Luca, Halmos, Gabor, Sha, Wei, Kovacs, Magdolna, Jaszberenyi, Miklos, He, Jinlin, Rick, Ferenc G., Popovics, Petra, Kanashiro-Takeuchi, Rosemeire, Hare, Joshua M., Block, Norman L., Zarandi, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745889/
https://ncbi.nlm.nih.gov/pubmed/24373935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2013.12.010
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