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Establishment of a novel therapeutic vector targeting the trigeminal ganglion in rats

BACKGROUND: In the pathogenesis of herpes simplex keratitis, herpes simplex virus type 1 (HSV-1) infection begins in corneal epithelium cells and then progresses through the sensory nerve endings and finally travels up forward to the trigeminal ganglion (TG), where it remains as latent virus. The av...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Xu, Kun, Pan, Shi-Yin, Song, Jin-Xin, Liu, Xian-Ning, An, Na, Zheng, Xuan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745838/
https://ncbi.nlm.nih.gov/pubmed/26893545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S96730
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