KCNQ channels in nociceptive cold-sensing trigeminal ganglion neurons as therapeutic targets for treating orofacial cold hyperalgesia

BACKGROUND: Hyperexcitability of nociceptive afferent fibers is an underlying mechanism of neuropathic pain and ion channels involved in neuronal excitability are potentially therapeutic targets. KCNQ channels, a subfamily of voltage-gated K(+) channels mediating M-currents, play a key role in neuro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Abd-Elsayed, Alaa A, Ikeda, Ryo, Jia, Zhanfeng, Ling, Jennifer, Zuo, Xiaozhuo, Li, Min, Gu, Jianguo G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4521366/
https://ncbi.nlm.nih.gov/pubmed/26227020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12990-015-0048-8
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados