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Targeting autophagy enhances the anti-tumoral action of crizotinib in ALK-positive anaplastic large cell lymphoma

Anaplastic Lymphoma Kinase-positive Anaplastic Large Cell Lymphomas (ALK+ ALCL) occur predominantly in children and young adults. Their treatment, based on aggressive chemotherapy, is not optimal since ALCL patients can still expect a 30% 2-year relapse rate. Tumor relapses are very aggressive and t...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Mitou, Géraldine, Frentzel, Julie, Desquesnes, Aurore, Le Gonidec, Sophie, AlSaati, Talal, Beau, Isabelle, Lamant, Laurence, Meggetto, Fabienne, Espinos, Estelle, Codogno, Patrice, Brousset, Pierre, Giuriato, Sylvie
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745787/
https://ncbi.nlm.nih.gov/pubmed/26338968
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