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NDRG1 promotes growth of hepatocellular carcinoma cells by directly interacting with GSK-3β and Nur77 to prevent β-catenin degradation

The N-myc downstream regulated gene 1 (NDRG1) is significantly associated with advanced tumor stages and poor survival of hepatocellular carcinoma (HCC), thereby implicating it as a potential target for HCC treatment. We aim to further understand its biological roles in hepatocarcinogenesis, as a me...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Lu, Wen-Jing, Chua, Mei-Sze, Wei, Wei, So, Samuel K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745767/
https://ncbi.nlm.nih.gov/pubmed/26359353
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