PECAM-1 Affects GSK-3β-Mediated β-Catenin Phosphorylation and Degradation

Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates a variety of endothelial and immune cell biological responses. PECAM-1-null mice exhibit prolonged and increased permeability after inflammatory insults. We observed that in PECAM-1-null endothelial cells (ECs), β-catenin remaine...

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Detalhes bibliográficos
Main Authors: Biswas, Purba, Canosa, Sandra, Schoenfeld, David, Schoenfeld, Jonathan, Li, Puyau, Cheas, Lydia C., Zhang, Jin, Cordova, Alfredo, Sumpio, Bauer, Madri, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698776/
https://ncbi.nlm.nih.gov/pubmed/16816383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051112
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