C1q modulates the response to TLR7 stimulation by pristane-primed macrophages: implications for pristane-induced lupus

The complement component C1q is known to play a controversial role in the pathogenesis of systemic lupus erythematosus (SLE), but the underlying mechanisms remain poorly understood. Intraperitoneal injection of pristane induces a lupus-like syndrome whose pathogenesis implicates the secretion of typ...

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Veröffentlicht in:J Immunol
Hauptverfasser: Carlucci, Francesco, Ishaque, Attia, Ling, Guang Sheng, Szajna, Marta, Sandison, Ann, Donatien, Philippe, Cook, H Terence, Botto, Marina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4745139/
https://ncbi.nlm.nih.gov/pubmed/26773156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401009
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