CSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q)

Mutations of CSNK1A1, a gene mapping to the commonly deleted region of the 5q‐ syndrome, have been recently described in patients with del(5q) myelodysplastic syndromes (MDS). Haploinsufficiency of Csnk1a1 in mice has been shown to result in β‐catenin activation and expansion of haematopoietic stem...

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Enregistré dans:
Détails bibliographiques
Publié dans:Br J Haematol
Auteurs principaux: Bello, Erica, Pellagatti, Andrea, Shaw, Jacqueline, Mecucci, Cristina, Kušec, Rajko, Killick, Sally, Giagounidis, Aristoteles, Raynaud, Sophie, Calasanz, María J., Fenaux, Pierre, Boultwood, Jacqueline
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Haematological Malignancy
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744770/
https://ncbi.nlm.nih.gov/pubmed/26085061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13563
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