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IRF4 and IRF8 act in CD11c(+) cells to regulate terminal differentiation of lung tissue dendritic cells()
Dendritic cells (DCs) initiate immune responses in barrier tissues including lung and skin. Conventional DC subsets, CD11b(−) (cDC1s) or CD11b(+) (cDC2s), arise via distinct networks of transcription factors involving IRF4 and IRF8 and are specialized for unique functional responses. Using mice in w...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4744567/ https://ncbi.nlm.nih.gov/pubmed/26746189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1501870 |
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