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IRF7 Regulates TLR2-Mediated Activation of Splenic CD11c(hi) Dendritic Cells

Members of the Interferon Regulatory Factor (IRF) family of transcription factors play an essential role in the development and function of the immune system. Here we investigated the role of IRF7 in the functional activation of conventional CD11c(hi) splenic dendritic cells (cDCs) in vitro and in v...

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Autors principals: Owens, Benjamin M. J., Moore, John W. J., Kaye, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398003/
https://ncbi.nlm.nih.gov/pubmed/22815909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041050
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