No SEVI-mediated enhancement of rectal HIV-1 transmission of HIV-1 in two humanized mouse cohorts

Amyloid fibrils from semen-derived peptide (SEVI) enhance HIV-1 infectivity in vitro but the ability of SEVI to mediate enhancement of HIV infection in vivo has not been tested. In this study we used immunodeficient mice reconstituted with human immune systems to test for in vivo enhancement of HIV-...

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Publicado no:Virology
Main Authors: Van Dis, Erik S, Moore, Tyler C., Lavender, Kerry J, Messer, Ronald J, Keppler, Oliver T, Verheyen, Jens, Dittmer, Ulf, Hasenkrug, Kim J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744509/
https://ncbi.nlm.nih.gov/pubmed/26609939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.11.005
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