Eomesodermin is Sufficient to Direct Type 1 Innate Lymphocyte Development into the Conventional Natural Killer Lineage

Type 1 innate lymphocytes comprise two developmentally divergent lineages, type 1 helper innate lymphoid cells (hILC1s) and conventional NK cells (cNKs). All type 1 innate lymphocytes (ILCs) express the transcription factor T-bet, but cNKs additionally express Eomesodermin (Eomes). We show that dele...

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Pubblicato in:J Immunol
Autori principali: Pikovskaya, Olga, Chaix, Julie, Rothman, Nyanza J., Collins, Amélie, Chen, Yen-Hua, Scipioni, Anna M., Vivier, Eric, Reiner, Steven L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744497/
https://ncbi.nlm.nih.gov/pubmed/26792802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502396
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