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Compliance Accelerates Relaxation in Muscle by Allowing Myosin Heads to Move Relative to Actin

The mechanisms that limit the speed at which striated muscles relax are poorly understood. This work presents, to our knowledge, novel simulations that show that the time course of relaxation is accelerated by interfilamentary movement resulting from series compliance; force drops faster when myosin...

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Bibliografiske detaljer
Udgivet i:Biophys J
Hovedforfatter: Campbell, Kenneth S.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744171/
https://ncbi.nlm.nih.gov/pubmed/26840730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.12.024
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