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NG2 PROTEOGLYCAN-DEPENDENT CONTRIBUTIONS OF PERICYTES AND MACROPHAGES TO BRAIN TUMOR VASCULARIZATION AND PROGRESSION

The NG2 proteoglycan promotes tumor growth as a component of both tumor and stromal cells. Using intracranial, NG2-negative B16F10 melanomas, we have investigated the importance of pericyte and macrophage NG2 in brain tumor progression. Reduced melanoma growth in myeloid-specific NG2 null (Mac-NG2ko...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Microcirculation
Hauptverfasser: Stallcup, William B., You, Weon-Kyoo, Kucharova, Karolina, Cejudo-Martin, Pilar, Yotsumoto, Fusanori
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744154/
https://ncbi.nlm.nih.gov/pubmed/26465118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/micc.12251
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