Antisense Transcripts Delimit Exonucleolytic Activity of the Mitochondrial 3′ Processome to Generate Guide RNAs

Small non-coding RNA biogenesis typically involves cleavage of structured precursor by RNase III-like endonucleases. However, guide RNAs that direct U-insertion/deletion mRNA editing in mitochondria of trypanosomes maintain 5′ triphosphate characteristic of the transcription initiation and possess a...

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Publicat a:Mol Cell
Autors principals: Suematsu, Takuma, Zhang, Liye, Aphasizheva, Inna, Monti, Stefano, Huang, Lan, Wang, Qi, Costello, Catherine E., Aphasizhev, Ruslan
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744118/
https://ncbi.nlm.nih.gov/pubmed/26833087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.01.004
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