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Blockage of the Ryanodine Receptor via Azumolene Does Not Prevent Mechanical Ventilation-Induced Diaphragm Atrophy

Mechanical ventilation (MV) is a life-saving intervention for patients in respiratory failure. However, prolonged MV causes the rapid development of diaphragm muscle atrophy, and diaphragmatic weakness may contribute to difficult weaning from MV. Therefore, developing a therapeutic countermeasure to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Talbert, Erin E., Smuder, Ashley J., Kwon, Oh Sung, Sollanek, Kurt J., Wiggs, Michael P., Powers, Scott K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4744044/
https://ncbi.nlm.nih.gov/pubmed/26849371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0148161
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