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Therapeutic Effects of an anti-ADAMTS-5 Antibody on Joint Damage and Mechanical Allodynia in a Murine Model of Osteoarthritis
OBJECTIVE: The primary goal of this study was to test the disease-modifying effect of blocking a disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS)-5 with a neutralizing monoclonal antibody (mAb) starting 4 weeks after destabilization of the medial meniscus (DMM) in the mouse. We...
Gorde:
| Argitaratua izan da: | Osteoarthritis Cartilage |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4743933/ https://ncbi.nlm.nih.gov/pubmed/26410555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2015.09.005 |
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