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Structure and stabilization of the Hendra virus F glycoprotein in its prefusion form

Hendra virus (HeV) is one of the two prototypical members of the Henipavirus genus of paramyxoviruses, which are designated biosafety level 4 (BSL-4) organisms due to the high mortality rate of Nipah virus (NiV) and HeV in humans. Paramyxovirus cell entry is mediated by the fusion protein, F, in res...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wong, Joyce J. W., Paterson, Reay G., Lamb, Robert A., Jardetzky, Theodore S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743799/
https://ncbi.nlm.nih.gov/pubmed/26712026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523303113
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