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Chronic Therapy with Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs with Advanced Heart Failure

BACKGROUND: Elamipretide (MTP-131), a novel mitochondria-targeting peptide, was shown to reduce infarct size in animals with myocardial infarction and improve renal function in pigs with acute and chronic kidney injury. This study examined the effects of chronic therapy with elamipretide on left ven...

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Bibliografische gegevens
Gepubliceerd in:Circ Heart Fail
Hoofdauteurs: Sabbah, Hani N., Gupta, Ramesh C., Kohli, Smita, Wang, Mengjun, Hachem, Souheila, Zhang, Kefei
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743543/
https://ncbi.nlm.nih.gov/pubmed/26839394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.115.002206
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