Llwytho...

Selectivity profiling of BCRP versus P-gp inhibition: from automated collection of polypharmacology data to multi-label learning

BACKGROUND: The human ATP binding cassette transporters Breast Cancer Resistance Protein (BCRP) and Multidrug Resistance Protein 1 (P-gp) are co-expressed in many tissues and barriers, especially at the blood–brain barrier and at the hepatocyte canalicular membrane. Understanding their interplay in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Cheminform
Prif Awduron: Montanari, Floriane, Zdrazil, Barbara, Digles, Daniela, Ecker, Gerhard F.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743411/
https://ncbi.nlm.nih.gov/pubmed/26855674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13321-016-0121-y
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!