Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease with a poor prognosis. Fibroblasts and myofibroblasts are the key cells in the fibrotic process. Recently two drugs, pirfenidone and nintedanib, were approved for clinical use as they are able to slow down the disease progr...

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Bibliografische gegevens
Gepubliceerd in:Respir Res
Hoofdauteurs: Lehtonen, Siri T., Veijola, Anniina, Karvonen, Henna, Lappi-Blanco, Elisa, Sormunen, Raija, Korpela, Saara, Zagai, Ulrika, Sköld, Magnus C., Kaarteenaho, Riitta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743320/
https://ncbi.nlm.nih.gov/pubmed/26846335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0328-5
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