Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease with a poor prognosis. Fibroblasts and myofibroblasts are the key cells in the fibrotic process. Recently two drugs, pirfenidone and nintedanib, were approved for clinical use as they are able to slow down the disease progr...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Respir Res
Egile Nagusiak: Lehtonen, Siri T., Veijola, Anniina, Karvonen, Henna, Lappi-Blanco, Elisa, Sormunen, Raija, Korpela, Saara, Zagai, Ulrika, Sköld, Magnus C., Kaarteenaho, Riitta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743320/
https://ncbi.nlm.nih.gov/pubmed/26846335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0328-5
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