Krüppel-like factor 4 expression in oral carcinoma cells and hypermethylation at the gene promoter

BACKGROUND: Krüppel-like factor 4 (KLF4) is a transcription factor regulating proliferation-differentiation balance of epithelium, and down-regulated in less-differentiated and advanced oral carcinomas. Although the expression is inactivated by the promoter hypermethylation in malignant tumor cells,...

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Detalhes bibliográficos
Publicado no:BMC Oral Health
Main Authors: Yamaguchi, Ayumi, Kuroyama, Karen, Tokura, Ayana, Saito, Atsushi, Arikawa, Huhga, Hasebe, Takahisa, Usui, Dai, Yamaguchi, Kosuke, Chiba, Tadashige, Imai, Kazushi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743192/
https://ncbi.nlm.nih.gov/pubmed/26847634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12903-016-0172-5
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