Essential role of mitogen-activated protein kinases in IL-17A-induced MMP-3 expression in human synovial sarcoma cells

BACKGROUND: The tumor cells were needed to rearrange the extracellular matrix (ECM) and reorganize their cytoskeleton to facilitate the cell motility during the tumor invasion. The proinflammatory cytokine interleukin-17A (IL-17A) is reported to up-regulate tumor invasiveness via ECM degradation by...

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Udgivet i:BMC Res Notes
Main Authors: Sakurai, Takuma, Yoshiga, Daigo, Ariyoshi, Wataru, Okinaga, Toshinori, Kiyomiya, Hiroyasu, Furuta, Junya, Yoshioka, Izumi, Tominaga, Kazuhiro, Nishihara, Tatsuji
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743089/
https://ncbi.nlm.nih.gov/pubmed/26850593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-016-1892-y
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