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Neuroimaging genetic risk for Alzheimer's disease in preclinical individuals: From candidate genes to polygenic approaches

Better characterization of the preclinical phase of Alzheimer's disease (AD) is needed in order to develop effective interventions. Neuropathological changes in AD, including neuronal loss and the formation of proteinaceous deposits, begin up to 20 years before the onset of clinical symptoms. A...

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Bibliographic Details
Published in:Biol Psychiatry Cogn Neurosci Neuroimaging
Main Authors: Harrison, Theresa M, Bookheimer, Susan Y
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743051/
https://ncbi.nlm.nih.gov/pubmed/26858991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpsc.2015.09.003
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